Improving the Expression and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers by Targeted Sequence Changes

Soluble, recombinant native-like envelope glycoprotein (Env) trimers of various human immunodeficiency virus type 1 (HIV-1) genotypes are being developed for structural studies and as vaccine candidates aimed at the induction of broadly neutralizing antibodies (bNAbs). The prototypic design is desig...

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Ringe, Rajesh P., Ozorowski, Gabriel, Yasmeen, Anila, Cupo, Albert, Cruz Portillo, Victor M., Pugach, Pavel, Golabek, Michael, Rantalainen, Kimmo, Holden, Lauren G., Cottrell, Christopher A., Wilson, Ian A., Sanders, Rogier W., Ward, Andrew B., Klasse, P. J., Moore, John P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2017
Aiheet:
Vaccines and Antiviral Agents
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446630/
https://ncbi.nlm.nih.gov/pubmed/28381572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00264-17
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