Neutralizing antibody and anti-retroviral drug sensitivities of HIV-1 isolates resistant to small molecule CCR5 inhibitors

Por Pugach, Pavel, Ketas, Thomas J., Michael, Elizabeth, Moore, John P.
Publicado em 2008

Simian Immunodeficiency Virus Interactions with Macaque Dendritic Cells

Por Teleshova, Natalia, Derby, Nina, Martinelli, Elena, Pugach, Pavel, Calenda, Giulia, Robbiani, Melissa
Publicado em 2013

Inhibition of Bacterial Superantigens by Peptides and Antibodies

Por Visvanathan, Kumar, Charles, Alain, Bannan, Jason, Pugach, Pavel, Kashfi, Khosrow, Zabriskie, John B.
Publicado em 2001

Inhibition of Bacterial Superantigens by Peptides and Antibodies

Por Visvanathan, Kumar, Charles, Alain, Bannan, Jason, Pugach, Pavel, Kashfi, Khosrow, Zabriskie, John B.
Publicado em 2002

Native Conformation and Canonical Disulfide Bond Formation Are Interlinked Properties of HIV-1 Env Glycoproteins

Por Go, Eden P., Cupo, Albert, Ringe, Rajesh, Pugach, Pavel, Moore, John P., Desaire, Heather
Publicado no J Virol (2016)

HIV-1 Clones Resistant to a Small Molecule CCR5 Inhibitor Use the Inhibitor-Bound Form of CCR5 for Entry

Por Pugach, Pavel, Marozsan, Andre J., Ketas, Thomas J., Landes, Elissa L., Moore, John P., Kuhmann, Shawn E.
Publicado em 2006

In Vivo Binding and Retention of CD4-Specific DARPin 57.2 in Macaques

Por Pugach, Pavel, Krarup, Anders, Gettie, Agegnehu, Kuroda, Marcelo, Blanchard, James, Piatak, Michael, Lifson, Jeffrey D., Trkola, Alexandra, Robbiani, Melissa
Publicado em 2010

Inefficient entry of vicriviroc-resistant HIV-1 via the inhibitor-CCR5 complex at low cell surface CCR5 densities

Por Pugach, Pavel, Ray, Neelanjana, Klasse, Per Johan, Ketas, Thomas J., Michael, Elizabeth, Doms, Robert W., Lee, Benhur, Moore, John P.
Publicado em 2009

Conformation-Dependent Recognition of HIV gp120 by Designed Ankyrin Repeat Proteins Provides Access to Novel HIV Entry Inhibitors

Por Mann, Axel, Friedrich, Nikolas, Krarup, Anders, Weber, Jacqueline, Stiegeler, Emanuel, Dreier, Birgit, Pugach, Pavel, Robbiani, Melissa, Riedel, Tina, Moehle, Kerstin, Robinson, John A., Rusert, Peter, Plückthun, Andreas, Trkola, Alexandra
Publicado em 2013

The Differential Sensitivity of Human and Rhesus Macaque CCR5 to Small-Molecule Inhibitors of Human Immunodeficiency Virus Type 1 Entry Is Explained by a Single Amino Acid Differen...

Por Billick, Erika, Seibert, Christoph, Pugach, Pavel, Ketas, Tom, Trkola, Alexandra, Endres, Michael J., Murgolo, Nicholas J., Coates, Elizabeth, Reyes, Gregory R., Baroudy, Bahige M., Sakmar, Thomas P., Moore, John P., Kuhmann, Shawn E.
Publicado em 2004

Genetic and Phenotypic Analyses of Human Immunodeficiency Virus Type 1 Escape from a Small-Molecule CCR5 Inhibitor

Por Kuhmann, Shawn E., Pugach, Pavel, Kunstman, Kevin J., Taylor, Joann, Stanfield, Robyn L., Snyder, Amy, Strizki, Julie M., Riley, Janice, Baroudy, Bahige M., Wilson, Ian A., Korber, Bette T., Wolinsky, Steven M., Moore, John P.
Publicado em 2004

Genetic and Phenotypic Analyses of Human Immunodeficiency Virus Type 1 Escape from a Small-Molecule CCR5 Inhibitor

Por Kuhmann, Shawn E., Pugach, Pavel, Kunstman, Kevin J., Taylor, Joann, Stanfield, Robyn L., Snyder, Amy, Strizki, Julie M., Riley, Janice, Baroudy, Bahige M., Wilson, Ian A., Korber, Bette T., Wolinsky, Steven M., Moore, John P.
Publicado em 2004

A Modified Zinc Acetate Gel, a Potential Nonantiretroviral Microbicide, Is Safe and Effective against Simian-Human Immunodeficiency Virus and Herpes Simplex Virus 2 Infection In Vi...

Por Kenney, Jessica, Rodríguez, Aixa, Kizima, Larisa, Seidor, Samantha, Menon, Radhika, Jean-Pierre, Ninochka, Pugach, Pavel, Levendosky, Keith, Derby, Nina, Gettie, Agegnehu, Blanchard, James, Piatak, Michael, Lifson, Jeffrey D., Paglini, Gabriela, Zydowsky, Thomas M., Robbiani, Melissa, Fernández Romero, José A.
Publicado em 2013

HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use

Por Trkola, Alexandra, Kuhmann, Shawn E., Strizki, Julie M., Maxwell, Elizabeth, Ketas, Tom, Morgan, Tom, Pugach, Pavel, Xu, Serena, Wojcik, Lisa, Tagat, Jayaram, Palani, Anandan, Shapiro, Sherry, Clader, John W., McCombie, Stuart, Reyes, Gregory R., Baroudy, Bahige M., Moore, John P.
Publicado em 2002

Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens

Por Julien, Jean-Philippe, Lee, Jeong Hyun, Ozorowski, Gabriel, Hua, Yuanzi, Torrents de la Peña, Alba, de Taeye, Steven W., Nieusma, Travis, Cupo, Albert, Yasmeen, Anila, Golabek, Michael, Pugach, Pavel, Klasse, P. J., Moore, John P., Sanders, Rogier W., Ward, Andrew B., Wilson, Ian A.
Publicado no Proc Natl Acad Sci U S A (2015)

Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C

Por Klasse, P. J., LaBranche, Celia C., Ketas, Thomas J., Ozorowski, Gabriel, Cupo, Albert, Pugach, Pavel, Ringe, Rajesh P., Golabek, Michael, van Gils, Marit J., Guttman, Miklos, Lee, Kelly K., Wilson, Ian A., Butera, Salvatore T., Ward, Andrew B., Montefiori, David C., Sanders, Rogier W., Moore, John P.
Publicado no PLoS Pathog (2016)

A Potent Combination Microbicide that Targets SHIV-RT, HSV-2 and HPV

Por Kizima, Larisa, Rodríguez, Aixa, Kenney, Jessica, Derby, Nina, Mizenina, Olga, Menon, Radhika, Seidor, Samantha, Zhang, Shimin, Levendosky, Keith, Jean-Pierre, Ninochka, Pugach, Pavel, Villegas, Guillermo, Ford, Brian E., Gettie, Agegnehu, Blanchard, James, Piatak, Michael, Lifson, Jeffrey D., Paglini, Gabriela, Teleshova, Natalia, Zydowsky, Thomas M., Robbiani, Melissa, Fernández-Romero, José A.
Publicado em 2014

A Native-Like SOSIP.664 Trimer Based on an HIV-1 Subtype B env Gene

Por Pugach, Pavel, Ozorowski, Gabriel, Cupo, Albert, Ringe, Rajesh, Yasmeen, Anila, de Val, Natalia, Derking, Ronald, Kim, Helen J., Korzun, Jacob, Golabek, Michael, de los Reyes, Kevin, Ketas, Thomas J., Julien, Jean-Philippe, Burton, Dennis R., Wilson, Ian A., Sanders, Rogier W., Klasse, P. J., Ward, Andrew B., Moore, John P.
Publicado no J Virol (2015)

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-120 interface

Por Huang, Jinghe, Kang, Byong H., Pancera, Marie, Lee, Jeong Hyun, Tong, Tommy, Feng, Yu, Georgiev, Ivelin S., Chuang, Gwo-Yu, Druz, Aliaksandr, Doria-Rose, Nicole A., Laub, Leo, Sliepen, Kwinten, van Gils, Marit J., de la Peña, Alba Torrents, Derking, Ronald, Klasse, Per-Johan, Migueles, Stephen A., Bailer, Robert T., Alam, Munir, Pugach, Pavel, Haynes, Barton F., Wyatt, Richard T., Sanders, Rogier W., Binley, James M., Ward, Andrew B., Mascola, John R., Kwong, Peter D., Connors, Mark
Publicado no Nature (2014)

Immunogenicity of stabilized HIV-1 envelope trimers with reduced exposure of non-neutralizing epitopes

Por de Taeye, Steven W., Ozorowski, Gabriel, de la Peña, Alba Torrents, Guttman, Miklos, Julien, Jean-Philippe, van den Kerkhof, Tom L.G.M., Burger, Judith A., Pritchard, Laura K., Pugach, Pavel, Yasmeen, Anila, Crampton, Jordan, Hu, Joyce, Bontjer, Ilja, Torres, Jonathan L., Arendt, Heather, DeStefano, Joanne, Koff, Wayne C., Schuitemaker, Hanneke, Eggink, Dirk, Berkhout, Ben, Dean, Hansi, LaBranche, Celia, Crotty, Shane, Crispin, Max, Montefiori, David C., Klasse, P. J., Lee, Kelly K., Moore, John P., Wilson, Ian A., Ward, Andrew B., Sanders, Rogier W.
Publicado no Cell (2015)