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Native Conformation and Canonical Disulfide Bond Formation Are Interlinked Properties of HIV-1 Env Glycoproteins

We investigated whether there is any association between a native-like conformation and the presence of only the canonical (i.e., native) disulfide bonds in the gp120 subunits of a soluble recombinant human immunodeficiency virus type 1 (HIV-1) envelope (Env) glycoprotein. We used a mass spectrometr...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Go, Eden P., Cupo, Albert, Ringe, Rajesh, Pugach, Pavel, Moore, John P., Desaire, Heather
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810632/
https://ncbi.nlm.nih.gov/pubmed/26719247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01953-15
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