Neutralizing antibody and anti-retroviral drug sensitivities of HIV-1 isolates resistant to small molecule CCR5 inhibitors

Por Pugach, Pavel, Ketas, Thomas J., Michael, Elizabeth, Moore, John P.
Publicado em 2008

Resistance to CCR5 inhibitors caused by sequence changes in the fusion peptide of HIV-1 gp41

Por Anastassopoulou, Cleo G., Ketas, Thomas J., Klasse, Per Johan, Moore, John P.
Publicado em 2009

Env-glycoprotein heterogeneity as a source of apparent synergy and enhanced cooperativity in inhibition of HIV-1 infection by neutralizing antibodies and entry inhibitors

Por Ketas, Thomas J., Holuigue, Sophie, Matthews, Katie, Moore, John P., Klasse, Per Johan
Publicado em 2011

Effects of sequence changes in the HIV-1 gp41 fusion peptide on CCR5 inhibitor resistance

Por Anastassopoulou, Cleo G., Ketas, Thomas J., Sanders, Rogier W., Klasse, Per Johan, Moore, John P.
Publicado em 2012

HIV-1 Clones Resistant to a Small Molecule CCR5 Inhibitor Use the Inhibitor-Bound Form of CCR5 for Entry

Por Pugach, Pavel, Marozsan, Andre J., Ketas, Thomas J., Landes, Elissa L., Moore, John P., Kuhmann, Shawn E.
Publicado em 2006

Resistance of a human immunodeficiency virus type 1 isolate to a small molecule CCR5 inhibitor can involve sequence changes in both gp120 and gp41

Por Anastassopoulou, Cleo G., Ketas, Thomas J., Depetris, Rafael S., Thomas, Antonia M., Klasse, Per Johan, Moore, John P.
Publicado em 2011

Protection of rhesus macaques from vaginal infection by vaginally delivered Maraviroc, an inhibitor of HIV-1 entry via the CCR5 co-receptor

Por Veazey, Ronald S., Ketas, Thomas J., Dufour, Jason, Moroney-Rasmussen, Terri, Green, Linda C., Klasse, P.J., Moore, John P.
Publicado em 2010

N-terminal substitutions in HIV-1 gp41 reduce the expression of non-trimeric envelope glycoproteins on the virus

Por Dey, Antu K., David, Kathryn B., Ray, Neelanjana, Ketas, Thomas J., Klasse, Per J., Doms, Robert W., Moore, John P.
Publicado em 2007

Inefficient entry of vicriviroc-resistant HIV-1 via the inhibitor-CCR5 complex at low cell surface CCR5 densities

Por Pugach, Pavel, Ray, Neelanjana, Klasse, Per Johan, Ketas, Thomas J., Michael, Elizabeth, Doms, Robert W., Lee, Benhur, Moore, John P.
Publicado em 2009

Structural and biological mimicry of protein surface recognition by α/β-peptide foldamers

Por Horne, W. Seth, Johnson, Lisa M., Ketas, Thomas J., Klasse, Per Johan, Lu, Min, Moore, John P., Gellman, Samuel H.
Publicado em 2009

Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligands

Por Ketas, Thomas J., Kuhmann, Shawn E., Palmer, Ashley, Zurita, Juan, He, Weijing, Ahuja, Sunil K., Klasse, Per Johan, Moore, John P.
Publicado em 2007

Potent, Broad-Spectrum Inhibition of Human Immunodeficiency Virus Type 1 by the CCR5 Monoclonal Antibody PRO 140

Por Trkola, Alexandra, Ketas, Thomas J., Nagashima, Kirsten A., Zhao, Lu, Cilliers, Tonie, Morris, Lynn, Moore, John P., Maddon, Paul J., Olson, William C.
Publicado em 2001

Enhancement of α-Helix Mimicry by an α/β-Peptide Foldamer via Incorporation of a Dense Ionic Side Chain Array

Por Johnson, Lisa M., Mortenson, David E., Yun, Hyun Gi, Horne, W. Seth, Ketas, Thomas J., Lu, Min, Moore, John P., Gellman, Samuel H.
Publicado em 2012

Human Immunodeficiency Virus Type 1 Attachment, Coreceptor, and Fusion Inhibitors Are Active against both Direct and trans Infection of Primary Cells

Por Ketas, Thomas J., Frank, Ines, Klasse, Per Johan, Sullivan, Brian M., Gardner, Jason P., Spenlehauer, Catherine, Nesin, Mirjana, Olson, William C., Moore, John P., Pope, Melissa
Publicado em 2003

Enzymatic removal of mannose moieties can increase the immune response to HIV-1 gp120 in vivo

Por Banerjee, Kaustuv, Andjelic, Sofija, Klasse, Per Johan, Kang, Yun, Sanders, Rogier W., Michael, Elizabeth, Durso, Robert J., Ketas, Thomas J., Olson, William C., Moore, John P.
Publicado em 2009

Addition of a cholesterol group to an HIV-1 peptide fusion inhibitor dramatically increases its antiviral potency

Por Ingallinella, Paolo, Bianchi, Elisabetta, Ladwa, Neal A., Wang, Ying-Jie, Hrin, Renee, Veneziano, Maria, Bonelli, Fabio, Ketas, Thomas J., Moore, John P., Miller, Michael D., Pessi, Antonello
Publicado em 2009

Partial protection against multiple RT-SHIV162P3 vaginal challenge of rhesus macaques by a silicone elastomer vaginal ring releasing the NNRTI MC1220

Por Fetherston, Susan M., Geer, Leslie, Veazey, Ronald S., Goldman, Laurie, Murphy, Diarmaid J., Ketas, Thomas J., Klasse, Per Johan, Blois, Sylvain, La Colla, Paolo, Moore, John P., Malcolm, R. Karl
Publicado em 2013

Partial protection against multiple RT-SHIV162P3 vaginal challenge of rhesus macaques by a silicone elastomer vaginal ring releasing the NNRTI MC1220

Por Fetherston, Susan M., Geer, Leslie, Veazey, Ronald S., Goldman, Laurie, Murphy, Diarmaid J., Ketas, Thomas J., Klasse, Per Johan, Blois, Sylvain, La Colla, Paolo, Moore, John P., Malcolm, R. Karl
Publicado em 2013

HIV-1 evades virus-specific IgG2 and IgA class switching by targeting systemic and intestinal B cells via long-range intercellular conduits

Por Xu, Weifeng, Santini, Paul A., Sullivan, John S., He, Bing, Shan, Meimei, Ball, Susan C., Dyer, Wayne B., Ketas, Thomas J., Chadburn, Amy, Cohen-Gould, Leona, Knowles, Daniel M., Chiu, April, Sanders, Rogier W., Chen, Kang, Cerutti, Andrea
Publicado em 2009

Sustained Release of the CCR5 Inhibitors CMPD167 and Maraviroc from Vaginal Rings in Rhesus Macaques

Por Malcolm, R. Karl, Veazey, Ronald S., Geer, Leslie, Lowry, Deborah, Fetherston, Susan M., Murphy, Diarmaid J., Boyd, Peter, Major, Ian, Shattock, Robin J., Klasse, Per Johan, Doyle, Lara A., Rasmussen, Kelsi K., Goldman, Laurie, Ketas, Thomas J., Moore, John P.
Publicado em 2012