Structural and biological mimicry of protein surface recognition by α/β-peptide foldamers

Unnatural oligomers that can mimic protein surfaces offer a potentially useful strategy for blocking biomedically important protein-protein interactions. Here we evaluate an approach based on combining α- and β-amino acid residues in the context of a polypeptide sequence from the HIV protein gp41, w...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Horne, W. Seth, Johnson, Lisa M., Ketas, Thomas J., Klasse, Per Johan, Lu, Min, Moore, John P., Gellman, Samuel H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2009
Gaiak:
Physical Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736470/
https://ncbi.nlm.nih.gov/pubmed/19706443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902663106
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