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α-Helix Mimicry with α/β-Peptides

We describe a general strategy for creating peptidic oligomers that have unnatural backbones but nevertheless adopt a conformation very similar to the α-helix. These oligomers contain both α- and β-amino acid residues (α/β-peptides). If the β content reaches 25–30% of the residue total, and the β re...

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Main Authors: Johnson, Lisa M., Gellman, Samuel H.
格式: Artigo
語言:Inglês
出版: 2013
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928965/
https://ncbi.nlm.nih.gov/pubmed/23422441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-394292-0.00019-9
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