EXTENDING FOLDAMER DESIGN BEYOND α-HELIX MIMICRY: α/β-PEPTIDE INHIBITORS OF VASCULAR ENDOTHELIAL GROWTH FACTOR SIGNALING

Diverse strategies have been explored to mimic the surface displayed by an α-helical segment of a protein, with the goal of creating inhibitors of helix-mediated protein-protein interactions. Many recognition surfaces on proteins, however, are topologically more complex and less regular than a singl...

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Bibliografische gegevens
Hoofdauteurs: Haase, Holly S., Peterson-Kaufman, Kimberly J., Lan Levengood, Sheeny K., Checco, James W., Murphy, William L., Gellman, Samuel H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551614/
https://ncbi.nlm.nih.gov/pubmed/22548447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja302469a
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