Targeting recognition surfaces on natural proteins with peptidic foldamers

por Checco, James W, Gellman, Samuel H
Publicado en Curr Opin Struct Biol (2016)

Iterative non-proteinogenic residue incorporation yields α/β-peptides with a helix-loop-helix tertiary structure and high affinity for VEGF

por Checco, James W., Gellman, Samuel H.
Publicado en Chembiochem (2017)

Non-targeted identification of D-amino acid-containing peptides through enzymatic screening, chiral amino acid analysis and LC-MS

por Tai, Hua-Chia, Checco, James W., Sweedler, Jonathan V.
Publicado en Methods Mol Biol (2018)

Differential Post-translational Amino Acid Isomerization Found Among Neuropeptides in Aplysia californica

por Mast, David H., Checco, James W., Sweedler, Jonathan V.
Publicado en ACS Chem Biol (2020)

Advancing d-amino acid-containing peptide discovery in the metazoan

por Mast, David H., Checco, James W., Sweedler, Jonathan V.
Publicado en Biochim Biophys Acta Proteins Proteom (2020)

Tumor Necrosis Factor-α Trimer Disassembly and Inactivation via Peptide-Small Molecule Synergy

por Checco, James W., Eddinger, Geoffrey A., Rettko, Nicholas J., Chartier, Alexander R., Gellman, Samuel H.
Publicado en ACS Chem Biol (2020)

Conformational Investigation of the Structure – Activity Relationship of GdFFD and Its Analogues on an Achatin-like Neuropeptide Receptor of Aplysia californica Involved in the Fee...

por Do, Thanh D., Checco, James W., Tro, Michael, Shea, Joan-Emma, Bowers, Michael T., Sweedler, Jonathan V.
Publicado en Phys Chem Chem Phys (2018)

Aplysia allatotropin-related peptide and its newly identified d-amino acid–containing epimer both activate a receptor and a neuronal target

por Checco, James W., Zhang, Guo, Yuan, Wang-ding, Le, Zi-wei, Jing, Jian, Sweedler, Jonathan V.
Publicado en J Biol Chem (2018)

STRUCTURE-GUIDED RATIONAL DESIGN OF α/β-PEPTIDE FOLDAMERS WITH HIGH AFFINITY FOR BCL-2 FAMILY PRO-SURVIVAL PROTEINS

por Smith, Brian J., Lee, Erinna F., Checco, James W., Evangelista, Marco, Gellman, Samuel H., Fairlie, W. Douglas
Publicado 2013

EXTENDING FOLDAMER DESIGN BEYOND α-HELIX MIMICRY: α/β-PEPTIDE INHIBITORS OF VASCULAR ENDOTHELIAL GROWTH FACTOR SIGNALING

por Haase, Holly S., Peterson-Kaufman, Kimberly J., Lan Levengood, Sheeny K., Checco, James W., Murphy, William L., Gellman, Samuel H.
Publicado 2012

Targeting diverse protein–protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold

por Checco, James W., Kreitler, Dale F., Thomas, Nicole C., Belair, David G., Rettko, Nicholas J., Murphy, William L., Forest, Katrina T., Gellman, Samuel H.
Publicado en Proc Natl Acad Sci U S A (2015)

Molecular and Physiological Characterization of a Receptor for d-Amino Acid-Containing Neuropeptides

por Checco, James W., Zhang, Guo, Yuan, Wang-ding, Yu, Ke, Yin, Si-yuan, Roberts-Galbraith, Rachel H., Yau, Peter M., Romanova, Elena V., Jing, Jian, Sweedler, Jonathan V.
Publicado en ACS Chem Biol (2018)

α/β-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells

por Checco, James W., Lee, Erinna F., Evangelista, Marco, Sleebs, Nerida J., Rogers, Kelly, Pettikiriarachchi, Anne, Kershaw, Nadia J., Eddinger, Geoffrey A., Belair, David G., Wilson, Julia L., Eller, Chelcie H., Raines, Ronald T., Murphy, William L., Smith, Brian J., Gellman, Samuel H., Fairlie, W. Douglas
Publicado en J Am Chem Soc (2015)