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Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C

We have investigated the immunogenicity in rabbits of native-like, soluble, recombinant SOSIP.664 trimers based on the env genes of four isolates of human immunodeficiency virus type 1 (HIV-1); specifically BG505 (clade A), B41 (clade B), CZA97 (clade C) and DU422 (clade C). The various trimers were...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Klasse, P. J., LaBranche, Celia C., Ketas, Thomas J., Ozorowski, Gabriel, Cupo, Albert, Pugach, Pavel, Ringe, Rajesh P., Golabek, Michael, van Gils, Marit J., Guttman, Miklos, Lee, Kelly K., Wilson, Ian A., Butera, Salvatore T., Ward, Andrew B., Montefiori, David C., Sanders, Rogier W., Moore, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023125/
https://ncbi.nlm.nih.gov/pubmed/27627672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005864
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