A Native-Like SOSIP.664 Trimer Based on an HIV-1 Subtype B env Gene

Recombinant trimeric mimics of the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (Env) spike should expose as many epitopes as possible for broadly neutralizing antibodies (bNAbs) but few, if any, for nonneutralizing antibodies (non-NAbs). Soluble, cleaved SOSIP.664 gp140 trimers...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Pugach, Pavel, Ozorowski, Gabriel, Cupo, Albert, Ringe, Rajesh, Yasmeen, Anila, de Val, Natalia, Derking, Ronald, Kim, Helen J., Korzun, Jacob, Golabek, Michael, de los Reyes, Kevin, Ketas, Thomas J., Julien, Jean-Philippe, Burton, Dennis R., Wilson, Ian A., Sanders, Rogier W., Klasse, P. J., Ward, Andrew B., Moore, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337520/
https://ncbi.nlm.nih.gov/pubmed/25589637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03473-14
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