A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies

A desirable but as yet unachieved property of a human immunodeficiency virus type 1 (HIV-1) vaccine candidate is the ability to induce broadly neutralizing antibodies (bNAbs). One approach to the problem is to create trimeric mimics of the native envelope glycoprotein (Env) spike that expose as many...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Sanders, Rogier W., Derking, Ronald, Cupo, Albert, Julien, Jean-Philippe, Yasmeen, Anila, de Val, Natalia, Kim, Helen J., Blattner, Claudia, de la Peña, Alba Torrents, Korzun, Jacob, Golabek, Michael, de los Reyes, Kevin, Ketas, Thomas J., van Gils, Marit J., King, C. Richter, Wilson, Ian A., Ward, Andrew B., Klasse, P. J., Moore, John P.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777863/
https://ncbi.nlm.nih.gov/pubmed/24068931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003618
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires