A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies

A desirable but as yet unachieved property of a human immunodeficiency virus type 1 (HIV-1) vaccine candidate is the ability to induce broadly neutralizing antibodies (bNAbs). One approach to the problem is to create trimeric mimics of the native envelope glycoprotein (Env) spike that expose as many...

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書誌詳細
主要な著者: Sanders, Rogier W., Derking, Ronald, Cupo, Albert, Julien, Jean-Philippe, Yasmeen, Anila, de Val, Natalia, Kim, Helen J., Blattner, Claudia, de la Peña, Alba Torrents, Korzun, Jacob, Golabek, Michael, de los Reyes, Kevin, Ketas, Thomas J., van Gils, Marit J., King, C. Richter, Wilson, Ian A., Ward, Andrew B., Klasse, P. J., Moore, John P.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777863/
https://ncbi.nlm.nih.gov/pubmed/24068931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003618
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