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Recognition of HIV-Inactivating Peptide Triazoles by the Recombinant Soluble Env Trimer, BG505 SOSIP.664
Peptide triazole (PT) antagonists interact with gp120 subunits of HIV-1 Env trimers to block host cell receptor interactions, trigger gp120 shedding, irreversibly inactivate virus and inhibit infection. Despite these enticing functions, understanding the structural mechanism of PT-Env trimer encount...
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| Publicado no: | Proteins |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389922/ https://ncbi.nlm.nih.gov/pubmed/28056499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25238 |
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