Lytic Inactivation of Human Immunodeficiency Virus by Dual Engagement of gp120 and gp41 Domains in the Virus Env Protein Trimer

We recently reported the discovery of a recombinant chimera, denoted DAVEI (dual-acting virucidal entry inhibitor), which is able to selectively cause specific and potent lytic inactivation of both pseudotyped and fully infectious human immunodeficiency virus (HIV-1) virions. The chimera is composed...

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Foilsithe in:Biochemistry
Main Authors: Parajuli, Bibek, Acharya, Kriti, Yu, Reina, Ngo, Brendon, Rashad, Adel A., Abrams, Cameron F., Chaiken, Irwin M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444381/
https://ncbi.nlm.nih.gov/pubmed/27731975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00570
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