Selective ALDH3A1 Inhibition by Benzimidazole Analogues Increase Mafosfamide Sensitivity in Cancer Cells

Autor Parajuli, Bibek, Fishel, Melissa L., Hurley, Thomas D.
Vydáno 2014

Roles of Conserved Tryptophans in Trimerization of HIV-1 Membrane-Proximal External Regions: Implications for Virucidal Design via Alchemical Free-Energy Molecular Simulations

Autor Gossert, Steven T., Parajuli, Bibek, Chaiken, Irwin, Abrams, Cameron F.
Vydáno v Proteins (2018)

Roles of variable linker length in dual acting virucidal entry inhibitors on HIV‐1 potency via on‐the‐fly free energy molecular simulations

Autor Gossert, Steven T., Parajuli, Bibek, Chaiken, Irwin, Abrams, Cameron F.
Vydáno v Protein Sci (2020)

Development of Selective Inhibitors for Human Aldehyde Dehydrogenase 3A1 (ALDH3A1) for the Enhancement of Cyclophosphamide Cytotoxicity

Autor Parajuli, Bibek, Georgiadis, Taxiarchis M., Fishel, Melissa L., Hurley, Thomas D.
Vydáno 2014

N,N-diethylaminobenzaldehyde (DEAB) as a substrate and mechanism-based inhibitor for human ALDH isoenzymes

Autor Morgan, Cynthia A., Parajuli, Bibek, Buchman, Cameron D., Dria, Karl, Hurley, Thomas D.
Vydáno v Chem Biol Interact (2014)

Discovery of Novel Regulators of Aldehyde Dehydrogenase Isoenzymes

Autor Parajuli, Bibek, Kimble-Hill, Ann C., Khanna, May, Ivanova, Yvelina, Meroueh, Samy, Hurley, Thomas D.
Vydáno 2011

Development of Selective Inhibitors for Aldehyde Dehydrogenases Based on Substituted Indole-2,3-diones

Autor Kimble-Hill, Ann C., Parajuli, Bibek, Chen, Che-Hong, Mochly-Rosen, Daria, Hurley, Thomas D.
Vydáno 2014

Lytic Inactivation of Human Immunodeficiency Virus by Dual Engagement of gp120 and gp41 Domains in the Virus Env Protein Trimer

Autor Parajuli, Bibek, Acharya, Kriti, Yu, Reina, Ngo, Brendon, Rashad, Adel A., Abrams, Cameron F., Chaiken, Irwin M.
Vydáno v Biochemistry (2016)

Restricted HIV-1 Env glycan engagement by lectin-reengineered DAVEI protein chimera is sufficient for lytic inactivation of the virus

Autor Parajuli, Bibek, Acharya, Kriti, Bach, Harry C., Parajuli, Bijay, Zhang, Shiyu, Smith, Amos B., Abrams, Cameron F., Chaiken, Irwin
Vydáno v Biochem J (2018)

Discovery of a Novel Class of Covalent Inhibitor for Aldehyde Dehydrogenases

Autor Khanna, May, Chen, Che-Hong, Kimble-Hill, Ann, Parajuli, Bibek, Perez-Miller, Samantha, Baskaran, Sulochanadevi, Kim, Jeewon, Dria, Karl, Vasiliou, Vasilis, Mochly-Rosen, Daria, Hurley, Thomas D.
Vydáno 2011