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Roles of variable linker length in dual acting virucidal entry inhibitors on HIV‐1 potency via on‐the‐fly free energy molecular simulations
The Dual‐Acting Virolytic Entry Inhibitors, or DAVEI's, are a class of recombinant chimera fusion proteins consisting of a lectin, a flexible polypeptide linker, and a fragment of the membrane‐proximal external region (MPER) of HIV‐1 gp41. DAVEIs trigger virolysis of HIV‐1 virions through inter...
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| Publicado no: | Protein Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7586904/ https://ncbi.nlm.nih.gov/pubmed/32926485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3949 |
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