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Development of Selective Inhibitors for Aldehyde Dehydrogenases Based on Substituted Indole-2,3-diones

[Image: see text] Aldehyde dehydrogenases (ALDH) participate in multiple metabolic pathways and have been indicated to play a role in several cancerous disease states. Our laboratory is interested in developing novel and selective ALDH inhibitors. We looked to further work recently published by deve...

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Detalhes bibliográficos
Main Authors: Kimble-Hill, Ann C., Parajuli, Bibek, Chen, Che-Hong, Mochly-Rosen, Daria, Hurley, Thomas D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954746/
https://ncbi.nlm.nih.gov/pubmed/24444054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm401377v
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