Mitochondrial aldehyde dehydrogenase and cardiac diseases

Por Chen, Che-Hong, Sun, Lihan, Mochly-Rosen, Daria
Publicado em 2010

ALDH2 polymorphism and alcohol-related cancers in Asians: a public health perspective

Por Chang, Jeffrey S., Hsiao, Jenn-Ren, Chen, Che-Hong
Publicado no J Biomed Sci (2017)

Cardioprotection from ischemia by a brief exposure to physiological levels of ethanol: Role of epsilon protein kinase C

Por Chen, Che-Hong, Gray, Mary O., Mochly-Rosen, Daria
Publicado em 1999

Pharmacological recruitment of aldehyde dehydrogenase 3A1 (ALDH3A1) to assist ALDH2 in acetaldehyde and ethanol metabolism in vivo

Por Chen, Che-Hong, Cruz, Leslie A., Mochly-Rosen, Daria
Publicado no Proc Natl Acad Sci U S A (2015)

Reactive aldehydes: an initial path to develop precision medicine for pain control

Por Zambelli, Vanessa O., Chen, Che-Hong, Gross, Eric R.
Publicado no Ann Transl Med (2015)

Organ-Specific Expression of Maize Adh1 Is Altered after a Mu Transposon Insertion

Por Chen, Che-Hong, Oishi, Karen K., Kloeckener-Gruissem, Barbara, Freeling, Michael
Publicado em 1987

Activation of aldehyde dehydrogenase 2 (ALDH2) confers cardioprotection in protein kinase C epsilon (PKCε) knockout mice

Por Budas, Grant R, Disatnik, Marie-Hélène, Chen, Che-Hong, Mochly-Rosen, Daria
Publicado em 2009

Targeting Aldehyde Dehydrogenase 2: New Therapeutic Opportunities

Por Chen, Che-Hong, Ferreira, Julio Cesar Batista, Gross, Eric R., Mochly-Rosen, Daria
Publicado em 2014

Aldehyde dehydrogenase 2 activation and coevolution of its εPKC-mediated phosphorylation sites

Por Nene, Aishwarya, Chen, Che-Hong, Disatnik, Marie-Hélène, Cruz, Leslie, Mochly-Rosen, Daria
Publicado no J Biomed Sci (2017)

Development of Selective Inhibitors for Aldehyde Dehydrogenases Based on Substituted Indole-2,3-diones

Por Kimble-Hill, Ann C., Parajuli, Bibek, Chen, Che-Hong, Mochly-Rosen, Daria, Hurley, Thomas D.
Publicado em 2014

Mitochondrial Reactive Oxygen Species at the Heart of the Matter: New Therapeutic Approaches for Cardiovascular Diseases

Por Kornfeld, Opher S., Hwang, Sunhee, Disatnik, Marie-Hélène, Chen, Che-Hong, Qvit, Nir, Mochly-Rosen, Daria
Publicado no Circ Res (2015)

Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant

Por Perez-Miller, Samantha, Younus, Hina, Vanam, Ram, Chen, Che-Hong, Mochly-Rosen, Daria, Hurley, Thomas D.
Publicado em 2010

Mitochondrial aldehyde dehydrogenase-2 activation prevents β-amyloid-induced endothelial cell dysfunction and restores angiogenesis

Por Solito, Raffaella, Corti, Federico, Chen, Che-Hong, Mochly-Rosen, Daria, Giachetti, Antonio, Ziche, Marina, Donnini, Sandra
Publicado em 2013

Mitigation of Radiation-Induced Dermatitis by Activation of Aldehyde Dehydrogenase 2 Using Topical Alda-1 in Mice

Por Ning, Shoucheng, Budas, Grant R., Churchill, Eric N., Chen, Che-Hong, Knox, Susan J., Mochly-Rosen, Daria
Publicado em 2012

Aldehyde dehydrogenase-2 regulates nociception in rodent models of acute inflammatory pain

Por Zambelli, Vanessa O., Gross, Eric R., Chen, Che-Hong, Gutierrez, Vanessa P., Cury, Yara, Mochly-Rosen, Daria
Publicado no Sci Transl Med (2014)

An Activator of Mutant and Wildtype Aldehyde Dehydrogenase Reduces Ischemic Damage to the Heart

Por Chen, Che-Hong, Budas, Grant R., Churchill, Eric N., Disatnik, Marie-Helene, Hurley, Thomas D., Mochly-Rosen, Daria
Publicado em 2008

PKC-ALDH2 Pathway Plays a Novel Role in Adipocyte Differentiation

Por Yu, Yu-Hsiang, Liao, Pei-Ru, Guo, Chien-Jung, Chen, Che-Hong, Mochly-Rosen, Daria, Chuang, Lee-Ming
Publicado no PLoS One (2016)

A Personalized Medicine Approach for Asian Americans with the Aldehyde Dehydrogenase 2*2 Variant

Por Gross, Eric R., Zambelli, Vanessa O., Small, Bryce A., Ferreira, Julio C.B., Chen, Che-Hong, Mochly-Rosen, Daria
Publicado no Annu Rev Pharmacol Toxicol (2014)

In vivo measurement of ALDH2 activity in rat liver ethanol model using dynamic MRSI of hyperpolarized [1-(13)C]pyruvate

Por Josan, Sonal, Xu, Tao, Yen, Yi-Fen, Hurd, Ralph, Ferreira, Julio, Chen, Che-Hong, Mochly-Rosen, Daria, Pfefferbaum, Adolf, Mayer, Dirk, Spielman, Daniel
Publicado em 2012

Sustained in vivo cardiac protection by a rationally designed peptide that causes ɛ protein kinase C translocation

Por Dorn, Gerald W., Souroujon, Miriam C., Liron, Tamar, Chen, Che-Hong, Gray, Mary O., Zhou, Hui Zhong, Csukai, Michael, Wu, Guangyu, Lorenz, John N., Mochly-Rosen, Daria
Publicado em 1999