An Activator of Mutant and Wildtype Aldehyde Dehydrogenase Reduces Ischemic Damage to the Heart

There is substantial interest in the development of drugs that limit the extent of ischemia-induced cardiac damage caused by myocardial infarction or by certain surgical procedures. Here an unbiased proteomic search identified mitochondrial aldehyde dehydrogenase 2 (ALDH2) as an enzyme whose activat...

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Hlavní autoři: Chen, Che-Hong, Budas, Grant R., Churchill, Eric N., Disatnik, Marie-Helene, Hurley, Thomas D., Mochly-Rosen, Daria
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741612/
https://ncbi.nlm.nih.gov/pubmed/18787169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1158554
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