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Activation of aldehyde dehydrogenase 2 (ALDH2) confers cardioprotection in protein kinase C epsilon (PKCε) knockout mice

Acute administration of ethanol can reduce cardiac ischemia/reperfusion injury. Previous studies demonstrated that the acute cytoprotective effect of ethanol on the myocardium is mediated by protein kinase C epsilon (PKCε). We recently identified aldehyde dehydrogenase 2 (ALDH2) as an PKCε substrate...

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Detalhes bibliográficos
Main Authors: Budas, Grant R, Disatnik, Marie-Hélène, Chen, Che-Hong, Mochly-Rosen, Daria
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837767/
https://ncbi.nlm.nih.gov/pubmed/19913552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.10.030
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