Mitochondrial import of PKCε is mediated by HSP90: a role in cardioprotection from ischaemia and reperfusion injury

AIMS: Protein kinase C epsilon (PKCε) is critical for cardiac protection from ischaemia and reperfusion (IR) injury. PKCε substrates that mediate cytoprotection reside in the mitochondria. However, the mechanism enabling mitochondrial translocation and import of PKCε to enable phosphorylation of the...

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Main Authors: Budas, Grant R., Churchill, Eric N., Disatnik, Marie-Hélène, Sun, Lihan, Mochly-Rosen, Daria
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2010
Ábhair:
Original Articles: Focus on Mitochondria in Cardiac Disease
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936125/
https://ncbi.nlm.nih.gov/pubmed/20558438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq154
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