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Aldehyde dehydrogenase 2 in cardiac protection: a new therapeutic target?
Mitochondrial aldehyde dehydrogenase 2 (ALDH2) is emerging as a key enzyme involved in cytoprotection in the heart. ALDH2 mediates both the detoxification of reactive aldehydes such as acetaldehyde and 4-hydroxy-2-nonenal (4-HNE) and the bioactivation of nitroglycerin (GTN) to nitric oxide (NO). In...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856486/ https://ncbi.nlm.nih.gov/pubmed/20005475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2009.09.003 |
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