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Discovery of a Novel Class of Covalent Inhibitor for Aldehyde Dehydrogenases
Human aldehyde dehydrogenases (ALDHs) comprise a family of 17 homologous enzymes that metabolize different biogenic and exogenic aldehydes. To date, there are relatively few general ALDH inhibitors that can be used to probe the contribution of this class of enzymes to particular metabolic pathways....
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3234859/ https://ncbi.nlm.nih.gov/pubmed/22021038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.293597 |
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