Immunological and chemical identification of a neurophysin-containing protein coded by messenger RNA from bovine hypothalamus

по Giudice, Linda C., Chaiken, Irwin M.
Опубликовано 1979

Quantitative Affinity Chromatography. Determination of Binding Constants by Elution with Competitive Inhibitors

по Dunn, Ben M., Chaiken, Irwin M.
Опубликовано 1974

Interaction with CD4 and Antibodies to CD4-Induced Epitopes of the Envelope gp120 from a Microglial Cell-Adapted Human Immunodeficiency Virus Type 1 Isolate

по Martín-García, Julio, Cocklin, Simon, Chaiken, Irwin M., González-Scarano, Francisco
Опубликовано 2005

Interleukin-5 Receptor Subunit Oligomerization and Rearrangement Revealed by Fluorescence Resonance Energy Transfer Imaging

по Zaks-Zilberman, Meirav, Harrington, Adrian E., Ishino, Tetsuya, Chaiken, Irwin M.
Опубликовано 2008

Lytic Inactivation of Human Immunodeficiency Virus by Dual Engagement of gp120 and gp41 Domains in the Virus Env Protein Trimer

по Parajuli, Bibek, Acharya, Kriti, Yu, Reina, Ngo, Brendon, Rashad, Adel A., Abrams, Cameron F., Chaiken, Irwin M.
Опубликовано в: Biochemistry (2016)

Use of the quartz crystal microbalance to monitor ligand-induced conformational rearrangements in HIV-1 envelope protein gp120

по Lee, Hyun-Su, Contarino, Mark, Umashankara, M., Schön, Arne, Freire, Ernesto, Smith, Amos B., Chaiken, Irwin M., Penn, Lynn S.
Опубликовано 2009

Monoclonal Antibody m18 Paratope Leading to Dual Receptor Antagonism of HIV-1 gp120()

по Gift, Syna Kuriakose, McFadden, Karyn, Zentner, Isaac J., Rajagopal, Srivats, Zhang, Mei-Yun, Dimitrov, Dimiter S., Chaiken, Irwin M.
Опубликовано 2011

Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding

по Wu, Hao, Myszka, David G., Tendian, Susan W., Brouillette, Christie G., Sweet, Ray W., Chaiken, Irwin M., Hendrickson, Wayne A.
Опубликовано 1996

Peptide Triazole Thiol Irreversibly Inactivates Metastable HIV-1 Env by Accessing Conformational Triggers Intrinsic to Virus–Cell Entry

по Ang, Charles Gotuaco, Carter, Erik, Haftl, Ann, Zhang, Shiyu, Rashad, Adel A., Kutzler, Michele, Abrams, Cameron F., Chaiken, Irwin M.
Опубликовано в: Microorganisms (2021)

Broad-Spectrum Anti-Human Immunodeficiency Virus (HIV) Potential of a Peptide HIV Type 1 Entry Inhibitor

по Cocklin, Simon, Gopi, Hosahudya, Querido, Bianca, Nimmagadda, Manideepthi, Kuriakose, Syna, Cicala, Claudia, Ajith, Sandya, Baxter, Sabine, Arthos, James, Martín-García, Julio, Chaiken, Irwin M.
Опубликовано 2007

Covalent Conjugation of a Peptide Triazole to HIV-1 gp120 Enables Intramolecular Binding Site Occupancy

по Emileh, Ali, Duffy, Caitlin, Holmes, Andrew P., Rosemary Bastian, Arangassery, Aneja, Rachna, Tuzer, Ferit, Rajagopal, Srivats, Li, Huiyuan, Abrams, Cameron F., Chaiken, Irwin M.
Опубликовано 2014

Introducing metallocene into a triazole peptide conjugate reduces its off-rate and enhances its affinity and antiviral potency for HIV-1 gp120

по Gopi, Hosahudya, Cocklin, Simon, Pirrone, Vanessa, McFadden, Karyn, Tuzer, Ferit, Zentner, Isaac, Ajith, Sandya, Baxter, Sabine, Jawanda, Navneet, Krebs, Fred C., Chaiken, Irwin M.
Опубликовано 2009

A model of the peptide triazole entry inhibitor binding to HIV-1 gp120 and mechanism of bridging sheet disruption

по Emileh, Ali, Tuzer, Ferit, Yeh, Herman, Umashankara, Muddegowda, Moreira, Diogo R. M., LaLonde, Judith M., Bewley, Carole A., Abrams, Cameron F., Chaiken, Irwin M.
Опубликовано 2013

Structure-Based Design, Synthesis and Validation of CD4-Mimetic Small Molecule Inhibitors of HIV-1 Entry: Conversion of a Viral Entry Agonist to an Antagonist

по Courter, Joel R., Madani, Navid, Sodroski, Joseph, Schön, Arne, Freire, Ernesto, Kwong, Peter D., Hendrickson, Wayne A., Chaiken, Irwin M., LaLonde, Judith M., Smith, Amos B.
Опубликовано 2014

Non-Natural Peptide Triazole Antagonists of HIV-1 Envelope gp120

по Kamanna, Kantharaju, Aneja, Rachna, Duffy, Caitlin, Kubinski, Pamela, Moreira, Diogo Rodrigo, Bailey, Lauren D, McFadden, Karyn, Schön, Arne, Holmes, Andrew, Tuzer, Ferit, Contarino, Mark, Freire, Ernesto, Chaiken, Irwin M
Опубликовано 2012

Conformational and Structural Features of HIV-1 gp120 Underlying Dual Receptor Antagonism by the Cross-Reactive Neutralizing Antibody, m18

по Gift, Syna Kuriakose, Zentner, Isaac J., Schön, Arne, McFadden, Karyn, Umashankara, M., Rajagopal, Srivats, Contarino, Mark, Duffy, Caitlin, Courter, Joel R., Zhang, Mei-Yun, Gershoni, Jonathan M., Cocklin, Simon, Dimitrov, Dimiter S., Smith, Amos B., Freire, Ernesto, Chaiken, Irwin M.
Опубликовано 2011

Abasic Phosphorothioate Oligomers Inhibit HIV-1 Reverse Transcription and Block Virus Transmission across Polarized Ectocervical Organ Cultures

по Fraietta, Joseph A., Mueller, Yvonne M., Lozenski, Karissa L., Ratner, Deena, Boesteanu, Alina C., Hancock, Aidan S., Lackman-Smith, Carol, Zentner, Isaac J., Chaiken, Irwin M., Chung, Suhman, LeGrice, Stuart F. J., Snyder, Beth A., Mankowski, Marie K., Jones, Natalie M., Hope, Jennifer L., Gupta, Phalguni, Anderson, Sharon H., Wigdahl, Brian, Katsikis, Peter D.
Опубликовано в: Antimicrob Agents Chemother (2014)