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Interleukin-5 Receptor Subunit Oligomerization and Rearrangement Revealed by Fluorescence Resonance Energy Transfer Imaging

Interleukin (IL)-5 exerts hematopoietic functions through binding to the IL-5 receptor subunits, α and βc. Specific assembly steps of full-length subunits as they occur in cell membranes, ultimately leading to receptor activation, are not well understood. We tracked the oligomerization of IL-5 recep...

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Detalhes bibliográficos
Main Authors: Zaks-Zilberman, Meirav, Harrington, Adrian E., Ishino, Tetsuya, Chaiken, Irwin M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442328/
https://ncbi.nlm.nih.gov/pubmed/18326494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710230200
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