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Ligand-induced Rearrangements of the GABA(B) Receptor Revealed by Fluorescence Resonance Energy Transfer

The γ-aminobutyric acid type B receptor (GABA(B)R), one of the family C G-protein-coupled receptor members, exists as a heterodimer comprised of subunits GB1 and GB2. To clarify the ligand-induced activation mechanism of the GABA(B)R, each subunit was fused with either Cerulean or enhanced yellow fl...

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Detalhes bibliográficos
Main Authors: Matsushita, Shinichi, Nakata, Hiroyasu, Kubo, Yoshihiro, Tateyama, Michihiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856234/
https://ncbi.nlm.nih.gov/pubmed/20129919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.077990
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