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Slow-Dissociation Effect of Common Signaling Subunit β on IL5 and GM-CSF Receptor Assembly
Receptor activation by IL5 and GM-CSF is a sequential process that depends on their interaction with a cytokine-specific subunit α and recruitment of a common signaling subunit β (βc). In order to elucidate the assembly dynamics of these receptor subunits, we performed kinetic interaction analysis o...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587307/ https://ncbi.nlm.nih.gov/pubmed/18294864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2007.12.010 |
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