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Slow-Dissociation Effect of Common Signaling Subunit β on IL5 and GM-CSF Receptor Assembly

Receptor activation by IL5 and GM-CSF is a sequential process that depends on their interaction with a cytokine-specific subunit α and recruitment of a common signaling subunit β (βc). In order to elucidate the assembly dynamics of these receptor subunits, we performed kinetic interaction analysis o...

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Main Authors: Ishino, Tetsuya, Harrington, Adrian E., Zaks-Zilberman, Meirav, Scibek, Jeffery J., Chaiken, Irwin
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587307/
https://ncbi.nlm.nih.gov/pubmed/18294864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2007.12.010
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