Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding

The T-cell antigen coreceptor CD4 also serves as the receptor for the envelope glycoprotein gp120 of HIV. Extensive mutational analysis of CD4 has implicated residues from a portion of the extracellular amino-terminal domain (D1) in gp120 binding. However, none of these proteins has been fully chara...

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Bibliografski detalji
Glavni autori: Wu, Hao, Myszka, David G., Tendian, Susan W., Brouillette, Christie G., Sweet, Ray W., Chaiken, Irwin M., Hendrickson, Wayne A.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences of the USA 1996
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC26350/
https://ncbi.nlm.nih.gov/pubmed/8986758
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