Attainment of target rifampicin concentrations in cerebrospinal fluid during treatment of tuberculous meningitis

Tekijä Mezochow, Alyssa, Thakur, Kiran T., Zentner, Isaac, Subbian, Selvakumar, Kagan, Leonid, Vinnard, Christopher
Julkaisussa Int J Infect Dis (2019)

A Pilot Study of Immune Activation and Rifampin Absorption in HIV-Infected Patients without Tuberculosis Infection: A Short Report

Tekijä Vinnard, Christopher, Manley, Isabel, Scott, Brittney, Bernui, Mariana, Adams, Joella, Varghese, Sheryl, Zentner, Isaac, Kutzler, Michele A.
Julkaisussa Tuberc Res Treat (2017)

Monoclonal Antibody m18 Paratope Leading to Dual Receptor Antagonism of HIV-1 gp120()

Tekijä Gift, Syna Kuriakose, McFadden, Karyn, Zentner, Isaac J., Rajagopal, Srivats, Zhang, Mei-Yun, Dimitrov, Dimiter S., Chaiken, Irwin M.
Julkaistu 2011

Discovery of a small-molecule antiviral targeting the HIV-1 matrix protein

Tekijä Zentner, Isaac, Sierra, Luz-Jeannette, Maciunas, Lina, Vinnik, Andrei, Fedichev, Peter, Mankowski, Marie K., Ptak, Roger G., Martín-García, Julio, Cocklin, Simon
Julkaistu 2012

Redox Imbalance and Oxidative DNA Damage During Isoniazid Treatment of HIV-Associated Tuberculosis: A Clinical and Translational Pharmacokinetic Study

Tekijä Zentner, Isaac, Back, Hyun-moon, Kagan, Leonid, Subbian, Selvakumar, Nagajyothi, Jyothi, Srivastava, Shashikant, Pasipanodya, Jotam, Gumbo, Tawanda, Bisson, Gregory P., Vinnard, Christopher
Julkaisussa Front Pharmacol (2020)

Structure of the complex between teicoplanin and a bacterial cell-wall peptide: use of a carrier-protein approach

Tekijä Economou, Nicoleta J., Zentner, Isaac J., Lazo, Edwin, Jakoncic, Jean, Stojanoff, Vivian, Weeks, Stephen D., Grasty, Kimberly C., Cocklin, Simon, Loll, Patrick J.
Julkaistu 2013

Active Core in a Triazole Peptide Dual Site Antagonist of HIV-1 gp120

Tekijä Umashankara, Muddegowda, McFadden, Karyn, Zentner, Isaac, Schön, Arne, Rajagopal, Srivats, Tuzer, Ferit, Kuriakose, Syna A, Contarino, Mark, LaLonde, Judith, Freire, Ernesto, Chaiken, Irwin
Julkaistu 2010

A carrier protein strategy yields the structure of dalbavancin

Tekijä Economou, Nicoleta J., Nahoum, Virginie, Weeks, Stephen D., Grasty, Kimberly C., Zentner, Isaac J., Townsend, Tracy M., Bhuiya, Mohammad W., Cocklin, Simon, Loll, Patrick J.
Julkaistu 2012

Introducing metallocene into a triazole peptide conjugate reduces its off-rate and enhances its affinity and antiviral potency for HIV-1 gp120

Tekijä Gopi, Hosahudya, Cocklin, Simon, Pirrone, Vanessa, McFadden, Karyn, Tuzer, Ferit, Zentner, Isaac, Ajith, Sandya, Baxter, Sabine, Jawanda, Navneet, Krebs, Fred C., Chaiken, Irwin M.
Julkaistu 2009

Identification of a Small-Molecule Inhibitor of HIV-1 Assembly that Targets the Phosphatidylinositol (4,5)-bisphosphate Binding Site of the HIV-1 Matrix Protein

Tekijä Zentner, Isaac, Sierra, Luz-Jeannette, Fraser, Ayesha K., Maciunas, Lina, Mankowski, Marie K., Vinnik, Andrei, Fedichev, Peter, Ptak, Roger G., Martín-García, Julio, Cocklin, Simon
Julkaisussa ChemMedChem (2013)

HIV-1 Env gp120 Structural Determinants for Peptide Triazole Dual Receptor Site Antagonism

Tekijä Tuzer, Ferit, Madani, Navid, Kamanna, Kantharaju, Zentner, Isaac, LaLonde, Judith, Holmes, Andrew, Upton, Elizabeth, Rajagopal, Srivats, McFadden, Karyn, Contarino, Mark, Sodroski, Joseph, Chaiken, Irwin
Julkaistu 2012

Urine colorimetry to detect Low rifampin exposure during tuberculosis therapy: a proof-of-concept study

Tekijä Zentner, Isaac, Schlecht, Hans P., Khensouvann, Lorna, Tamuhla, Neo, Kutzler, Michele, Ivaturi, Vijay, Pasipanodya, Jotam G., Gumbo, Tawanda, Peloquin, Charles A., Bisson, Gregory P., Vinnard, Christopher
Julkaisussa BMC Infect Dis (2016)

Determination of Rifampin Concentrations by Urine Colorimetry and Mobile Phone Readout for Personalized Dosing in Tuberculosis Treatment

Tekijä Szipszky, Claire, Van Aartsen, Daniel, Criddle, Sarah, Rao, Prakruti, Zentner, Isaac, Justine, Museveni, Mduma, Estomih, Mpagama, Stellah, Al-Shaer, Mohammad H, Peloquin, Charles, Thomas, Tania A, Vinnard, Christopher, Heysell, Scott K
Julkaisussa J Pediatric Infect Dis Soc (2020)

An Optimized, Synthetic DNA Vaccine Encoding the Toxin A and Toxin B Receptor Binding Domains of Clostridium difficile Induces Protective Antibody Responses In Vivo

Tekijä Baliban, Scott M., Michael, Amanda, Shammassian, Berje, Mudakha, Shikata, Khan, Amir S., Cocklin, Simon, Zentner, Isaac, Latimer, Brian P., Bouillaut, Laurent, Hunter, Meredith, Marx, Preston, Sardesai, Niranjan Y., Welles, Seth L., Jacobson, Jeffrey M., Weiner, David B., Kutzler, Michele A.
Julkaistu 2014

Structural Determinants for Affinity Enhancement of a Dual Antagonist Peptide Entry Inhibitor of Human Immunodeficiency Virus Type-1

Tekijä Gopi, Hosahudya, Umashankara, M., Pirrone, Vanessa, LaLonde, Judith, Madani, Navid, Tuzer, Ferit, Baxter, Sabine, Zentner, Isaac, Cocklin, Simon, Jawanda, Navneet, Miller, Shendra R., Schön, Arne, Klein, Jeffrey C., Freire, Ernesto, Krebs, Fred C., Smith, Amos B., Sodroski, Joseph, Chaiken, Irwin
Julkaistu 2008

Conformational and Structural Features of HIV-1 gp120 Underlying Dual Receptor Antagonism by the Cross-Reactive Neutralizing Antibody, m18

Tekijä Gift, Syna Kuriakose, Zentner, Isaac J., Schön, Arne, McFadden, Karyn, Umashankara, M., Rajagopal, Srivats, Contarino, Mark, Duffy, Caitlin, Courter, Joel R., Zhang, Mei-Yun, Gershoni, Jonathan M., Cocklin, Simon, Dimitrov, Dimiter S., Smith, Amos B., Freire, Ernesto, Chaiken, Irwin M.
Julkaistu 2011

IgG Binding Characteristics of Rhesus Macaque FcγR

Tekijä Chan, Ying N., Boesch, Austin W., Osei-Owusu, Nana Y., Emileh, Ali, Crowley, Andrew R., Cocklin, Sarah L., Finstad, Samantha L., Linde, Caitlyn H., Howell, Rebecca A., Zentner, Isaac, Cocklin, Simon, Miles, Adam R., Eckman, Joshua W., Alter, Galit, Schmitz, Joern E., Ackerman, Margaret E.
Julkaisussa J Immunol (2016)

Inhibiting Early-Stage Events in HIV-1 Replication by Small-Molecule Targeting of the HIV-1 Capsid

Tekijä Kortagere, Sandhya, Madani, Navid, Mankowski, Marie K., Schön, Arne, Zentner, Isaac, Swaminathan, Gokul, Princiotto, Amy, Anthony, Kevin, Oza, Apara, Sierra, Luz-Jeannette, Passic, Shendra R., Wang, Xiaozhao, Jones, David M., Stavale, Eric, Krebs, Fred C., Martín-García, Julio, Freire, Ernesto, Ptak, Roger G., Sodroski, Joseph, Cocklin, Simon, Smith, Amos B.
Julkaistu 2012

Abasic Phosphorothioate Oligomers Inhibit HIV-1 Reverse Transcription and Block Virus Transmission across Polarized Ectocervical Organ Cultures

Tekijä Fraietta, Joseph A., Mueller, Yvonne M., Lozenski, Karissa L., Ratner, Deena, Boesteanu, Alina C., Hancock, Aidan S., Lackman-Smith, Carol, Zentner, Isaac J., Chaiken, Irwin M., Chung, Suhman, LeGrice, Stuart F. J., Snyder, Beth A., Mankowski, Marie K., Jones, Natalie M., Hope, Jennifer L., Gupta, Phalguni, Anderson, Sharon H., Wigdahl, Brian, Katsikis, Peter D.
Julkaisussa Antimicrob Agents Chemother (2014)