Active Core in a Triazole Peptide Dual Site Antagonist of HIV-1 gp120

In an effort to identify broadly active inhibitors of HIV-1 entry into host cells, we had previously reported a family of dodecamer triazole-peptide conjugates with nanomolar affinity for viral surface protein gp120. This class of peptides exhibits potent antiviral activity and the capacity to simul...

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Bibliographic Details
Main Authors: Umashankara, Muddegowda, McFadden, Karyn, Zentner, Isaac, Schön, Arne, Rajagopal, Srivats, Tuzer, Ferit, Kuriakose, Syna A, Contarino, Mark, LaLonde, Judith, Freire, Ernesto, Chaiken, Irwin
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035117/
https://ncbi.nlm.nih.gov/pubmed/20677318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201000222
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