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HIV-1 Env gp120 Structural Determinants for Peptide Triazole Dual Receptor Site Antagonism

Despite advances in HIV therapy, viral resistance and side-effects with current drug regimens require targeting new components of the virus. Dual antagonist peptide triazoles (PT) are a novel class of HIV-1 inhibitors that specifically target the gp120 component of the viral spike and inhibit its in...

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Main Authors: Tuzer, Ferit, Madani, Navid, Kamanna, Kantharaju, Zentner, Isaac, LaLonde, Judith, Holmes, Andrew, Upton, Elizabeth, Rajagopal, Srivats, McFadden, Karyn, Contarino, Mark, Sodroski, Joseph, Chaiken, Irwin
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731144/
https://ncbi.nlm.nih.gov/pubmed/23011758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24184
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