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Monoclonal Antibody m18 Paratope Leading to Dual Receptor Antagonism of HIV-1 gp120()
We sought to identify sequences in the monoclonal antibody m18 complementarity determining regions (CDRs) that are responsible for its interaction with HIV-1 gp120 and inhibition of the envelope receptor binding sites. In the accompanying paper, we reported that m18 inhibits CD4 binding through a no...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3499988/ https://ncbi.nlm.nih.gov/pubmed/21417283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101161j |
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