Attainment of target rifampicin concentrations in cerebrospinal fluid during treatment of tuberculous meningitis

OBJECTIVE: There is considerable uncertainty regarding the optimal use of rifampicin for the treatment of tuberculous (TB) meningitis. A pharmacokinetic modeling and simulation study of rifampicin concentrations in cerebrospinal fluid (CSF) during TB meningitis treatment was performed in this study....

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Bibliographic Details
Published in:Int J Infect Dis
Main Authors: Mezochow, Alyssa, Thakur, Kiran T., Zentner, Isaac, Subbian, Selvakumar, Kagan, Leonid, Vinnard, Christopher
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6666413/
https://ncbi.nlm.nih.gov/pubmed/31051278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijid.2019.04.026
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