Guiding the Immune Response against Influenza Virus Hemagglutinin toward the Conserved Stalk Domain by Hyperglycosylation of the Globular Head Domain

Por Eggink, Dirk, Goff, Peter H., Palese, Peter
Publicado em 2014

Resistance of Human Immunodeficiency Virus Type 1 to a Third-Generation Fusion Inhibitor Requires Multiple Mutations in gp41 and Is Accompanied by a Dramatic Loss of gp41 Function

Por Eggink, Dirk, Bontjer, Ilja, Langedijk, Johannes P. M., Berkhout, Ben, Sanders, Rogier W.
Publicado em 2011

A Pan-H1 Anti-Hemagglutinin Monoclonal Antibody with Potent Broad-Spectrum Efficacy In Vivo

Por Tan, Gene S., Krammer, Florian, Eggink, Dirk, Kongchanagul, Alita, Moran, Thomas M., Palese, Peter
Publicado em 2012

In Vivo Bioluminescent Imaging of Influenza A Virus Infection and Characterization of Novel Cross-Protective Monoclonal Antibodies

Por Heaton, Nicholas S., Leyva-Grado, Victor H., Tan, Gene S., Eggink, Dirk, Hai, Rong, Palese, Peter
Publicado em 2013

Stabilized HIV-1 Envelope Glycoprotein Trimers Lacking the V1V2 Domain, Obtained by Virus Evolution

Por Bontjer, Ilja, Melchers, Mark, Eggink, Dirk, David, Kathryn, Moore, John P., Berkhout, Ben, Sanders, Rogier W.
Publicado em 2010

HIV-1 N-Glycan Composition Governs a Balance between Dendritic Cell-Mediated Viral Transmission and Antigen Presentation

Por van Montfort, Thijs, Eggink, Dirk, Boot, Maikel, Tuen, Michael, Hioe, Catarina E., Berkhout, Ben, Sanders, Rogier W.
Publicado em 2011

Adjuvants and Immunization Strategies to Induce Influenza Virus Hemagglutinin Stalk Antibodies

Por Goff, Peter H., Eggink, Dirk, Seibert, Christopher W., Hai, Rong, Martínez-Gil, Luis, Krammer, Florian, Palese, Peter
Publicado em 2013

Selection of T1249-Resistant Human Immunodeficiency Virus Type 1 Variants

Por Eggink, Dirk, Baldwin, Christopher E., Deng, Yiqun, Langedijk, Johannes P. M., Lu, Min, Sanders, Rogier W., Berkhout, Ben
Publicado em 2008

Role of Complex Carbohydrates in Human Immunodeficiency Virus Type 1 Infection and Resistance to Antibody Neutralization

Por Binley, James M., Ban, Yih-En Andrew, Crooks, Emma T., Eggink, Dirk, Osawa, Keiko, Schief, William R., Sanders, Rogier W.
Publicado em 2010

Influenza Viruses Expressing Chimeric Hemagglutinins: Globular Head and Stalk Domains Derived from Different Subtypes

Por Hai, Rong, Krammer, Florian, Tan, Gene S., Pica, Natalie, Eggink, Dirk, Maamary, Jad, Margine, Irina, Albrecht, Randy A., Palese, Peter
Publicado em 2012

Detailed Mechanistic Insights into HIV-1 Sensitivity to Three Generations of Fusion Inhibitors

Por Eggink, Dirk, Langedijk, Johannes P. M., Bonvin, Alexandre M. J. J., Deng, Yiqun, Lu, Min, Berkhout, Ben, Sanders, Rogier W.
Publicado em 2009

HIV-1 Escape from a Peptidic Anchor Inhibitor through Stabilization of the Envelope Glycoprotein Spike

Por Eggink, Dirk, de Taeye, Steven W., Bontjer, Ilja, Klasse, Per Johan, Langedijk, Johannes P. M., Berkhout, Ben, Sanders, Rogier W.
Publicado no J Virol (2016)

Inhibition of Arenavirus by A3, a Pyrimidine Biosynthesis Inhibitor

Por Ortiz-Riaño, Emilio, Ngo, Nhi, Devito, Stefanie, Eggink, Dirk, Munger, Joshua, Shaw, Megan L., de la Torre, Juan Carlos, Martínez-Sobrido, Luis
Publicado em 2014

Optimization of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins with V1/V2 Deleted, Using Virus Evolution

Por Bontjer, Ilja, Land, Aafke, Eggink, Dirk, Verkade, Erwin, Tuin, Kiki, Baldwin, Chris, Pollakis, Georgios, Paxton, William A., Braakman, Ineke, Berkhout, Ben, Sanders, Rogier W.
Publicado em 2009

Occluding the Mannose Moieties on Human Immunodeficiency Virus Type 1 gp120 with Griffithsin Improves the Antibody Responses to Both Proteins in Mice

Por Banerjee, Kaustuv, Michael, Elizabeth, Eggink, Dirk, van Montfort, Thijs, Lasnik, Amanda B., Palmer, Kenneth E., Sanders, Rogier W., Moore, John P., Klasse, Per Johan
Publicado em 2012

Comparative Immunogenicity of Evolved V1V2-Deleted HIV-1 Envelope Glycoprotein Trimers

Por Bontjer, Ilja, Melchers, Mark, Tong, Tommy, van Montfort, Thijs, Eggink, Dirk, Montefiori, David, Olson, William C., Moore, John P., Binley, James M., Berkhout, Ben, Sanders, Rogier W.
Publicado em 2013

A stabilized HIV-1 envelope glycoprotein trimer fused to CD40 ligand targets and activates dendritic cells

Por Melchers, Mark, Matthews, Katie, de Vries, Robert P, Eggink, Dirk, van Montfort, Thijs, Bontjer, Ilja, van de Sandt, Carolien, David, Kathryn, Berkhout, Ben, Moore, John P, Sanders, Rogier W
Publicado em 2011

Recombinant IgA Is Sufficient To Prevent Influenza Virus Transmission in Guinea Pigs

Por Seibert, Christopher W., Rahmat, Saad, Krause, Jens C., Eggink, Dirk, Albrecht, Randy A., Goff, Peter H., Krammer, Florian, Duty, J. Andrew, Bouvier, Nicole M., García-Sastre, Adolfo, Palese, Peter
Publicado em 2013

The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion

Por Sanders, Rogier W, van Anken, Eelco, Nabatov, Alexei A, Liscaljet, I Marije, Bontjer, Ilja, Eggink, Dirk, Melchers, Mark, Busser, Els, Dankers, Martijn M, Groot, Fedde, Braakman, Ineke, Berkhout, Ben, Paxton, William A
Publicado em 2008

Glycosylations in the globular head of the hemagglutinin protein modulate the virulence and antigenic properties of the H1N1 influenza viruses

Por Medina, Rafael A., Stertz, Silke, Manicassamy, Balaji, Zimmermann, Petra, Sun, Xiangjie, Albrecht, Randy A., Uusi-Kerttula, Hanni, Zagordi, Osvaldo, Belshe, Robert B., Frey, Sharon E., Eggink, Dirk, Tumpey, Terrence M., García-Sastre, Adolfo
Publicado em 2013