The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion

BACKGROUND: The HIV-1 envelope glycoprotein gp120, which mediates viral attachment to target cells, consists for ~50% of sugar, but the role of the individual sugar chains in various aspects of gp120 folding and function is poorly understood. Here we studied the role of the carbohydrate at position...

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Main Authors: Sanders, Rogier W, van Anken, Eelco, Nabatov, Alexei A, Liscaljet, I Marije, Bontjer, Ilja, Eggink, Dirk, Melchers, Mark, Busser, Els, Dankers, Martijn M, Groot, Fedde, Braakman, Ineke, Berkhout, Ben, Paxton, William A
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262092/
https://ncbi.nlm.nih.gov/pubmed/18237398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-5-10
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