Optimization of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins with V1/V2 Deleted, Using Virus Evolution

The human immunodeficiency virus type 1 envelope glycoprotein (Env) complex is the principal focus of neutralizing antibody-based vaccines. The functional Env complex is a trimer consisting of six individual subunits: three gp120 molecules and three gp41 molecules. The individual subunits have prove...

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Autori principali: Bontjer, Ilja, Land, Aafke, Eggink, Dirk, Verkade, Erwin, Tuin, Kiki, Baldwin, Chris, Pollakis, Georgios, Paxton, William A., Braakman, Ineke, Berkhout, Ben, Sanders, Rogier W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612307/
https://ncbi.nlm.nih.gov/pubmed/18922866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01404-08
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