HIV-1 Escape from a Peptidic Anchor Inhibitor through Stabilization of the Envelope Glycoprotein Spike

The trimeric HIV-1 envelope glycoprotein spike (Env) mediates viral entry into cells by using a spring-loaded mechanism that allows for the controlled insertion of the Env fusion peptide into the target membrane, followed by membrane fusion. Env is the focus of vaccine research aimed at inducing pro...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Eggink, Dirk, de Taeye, Steven W., Bontjer, Ilja, Klasse, Per Johan, Langedijk, Johannes P. M., Berkhout, Ben, Sanders, Rogier W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110188/
https://ncbi.nlm.nih.gov/pubmed/27654295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01616-16
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