HIV-1 Escape from a Peptidic Anchor Inhibitor through Stabilization of the Envelope Glycoprotein Spike

The trimeric HIV-1 envelope glycoprotein spike (Env) mediates viral entry into cells by using a spring-loaded mechanism that allows for the controlled insertion of the Env fusion peptide into the target membrane, followed by membrane fusion. Env is the focus of vaccine research aimed at inducing pro...

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Vydáno v:J Virol
Hlavní autoři: Eggink, Dirk, de Taeye, Steven W., Bontjer, Ilja, Klasse, Per Johan, Langedijk, Johannes P. M., Berkhout, Ben, Sanders, Rogier W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110188/
https://ncbi.nlm.nih.gov/pubmed/27654295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01616-16
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