HIV-1 Escape from a Peptidic Anchor Inhibitor through Stabilization of the Envelope Glycoprotein Spike

The trimeric HIV-1 envelope glycoprotein spike (Env) mediates viral entry into cells by using a spring-loaded mechanism that allows for the controlled insertion of the Env fusion peptide into the target membrane, followed by membrane fusion. Env is the focus of vaccine research aimed at inducing pro...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Eggink, Dirk, de Taeye, Steven W., Bontjer, Ilja, Klasse, Per Johan, Langedijk, Johannes P. M., Berkhout, Ben, Sanders, Rogier W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110188/
https://ncbi.nlm.nih.gov/pubmed/27654295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01616-16
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