Only Five of 10 Strictly Conserved Disulfide Bonds Are Essential for Folding and Eight for Function of the HIV-1 Envelope Glycoprotein

Protein folding in the endoplasmic reticulum goes hand in hand with disulfide bond formation, and disulfide bonds are considered key structural elements for a protein's folding and function. We used the HIV-1 Envelope glycoprotein to examine in detail the importance of its 10 completely conserv...

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Main Authors: van Anken, Eelco, Sanders, Rogier W., Liscaljet, I. Marije, Land, Aafke, Bontjer, Ilja, Tillemans, Sonja, Nabatov, Alexey A., Paxton, William A., Berkhout, Ben, Braakman, Ineke
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2555952/
https://ncbi.nlm.nih.gov/pubmed/18653472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-12-1282
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