Influenza Viruses Expressing Chimeric Hemagglutinins: Globular Head and Stalk Domains Derived from Different Subtypes

The influenza virus hemagglutinin molecule possesses a globular head domain that mediates receptor binding and a stalk domain at the membrane-proximal region. We generated functional influenza viruses expressing chimeric hemagglutinins encompassing a variety of globular head and stalk combinations,...

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Bibliographic Details
Main Authors: Hai, Rong, Krammer, Florian, Tan, Gene S., Pica, Natalie, Eggink, Dirk, Maamary, Jad, Margine, Irina, Albrecht, Randy A., Palese, Peter
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347257/
https://ncbi.nlm.nih.gov/pubmed/22398287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00137-12
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