Comparative Immunogenicity of Evolved V1V2-Deleted HIV-1 Envelope Glycoprotein Trimers

Despite almost 30 years of research, no effective vaccine has yet been developed against HIV-1. Probably such a vaccine would need to induce both an effective T cell and antibody response. Any vaccine component focused on inducing humoral immunity requires the HIV-1 envelope (Env) glycoprotein compl...

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Autors principals: Bontjer, Ilja, Melchers, Mark, Tong, Tommy, van Montfort, Thijs, Eggink, Dirk, Montefiori, David, Olson, William C., Moore, John P., Binley, James M., Berkhout, Ben, Sanders, Rogier W.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694020/
https://ncbi.nlm.nih.gov/pubmed/23840716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067484
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