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Occluding the Mannose Moieties on Human Immunodeficiency Virus Type 1 gp120 with Griffithsin Improves the Antibody Responses to Both Proteins in Mice

To assess the influence of mannosylated glycans on the immunogenicity of human immunodeficiency virus type 1 (HIV-1) Env proteins, we immunized mice with monomeric gp120 in the presence and absence of the mannose-binding protein, griffithsin (GRFT). For comparison, other groups of mice received the...

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Hlavní autoři: Banerjee, Kaustuv, Michael, Elizabeth, Eggink, Dirk, van Montfort, Thijs, Lasnik, Amanda B., Palmer, Kenneth E., Sanders, Rogier W., Moore, John P., Klasse, Per Johan
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275927/
https://ncbi.nlm.nih.gov/pubmed/21793733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2011.0101
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