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Env exceptionalism – Why are HIV-1 Env glycoproteins atypical immunogens?
Recombinant HIV-1 envelope glycoproteins (Env) of ever increasing sophistication have been evaluated as vaccine candidates for over 30 years. Structurally defined mimics of native trimeric Env (e.g., SOSIP trimers) present multiple epitopes for broadly neutralizing Abs (bNAbs) and their germline pre...
Gorde:
| Argitaratua izan da: | Cell Host Microbe |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7187920/ https://ncbi.nlm.nih.gov/pubmed/32272076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.03.018 |
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