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Short Communication: Virion Aggregation by Neutralizing and Nonneutralizing Antibodies to the HIV-1 Envelope Glycoprotein

We used dynamic light scattering to detect aggregation of HIV-1 virions by antibodies (IgG) to the viral envelope glycoprotein (Env). Virions of different strains were inactivated by 2,2′-dithiodipyridine (AT-2), a procedure that abrogates infectivity but preserves the native antigenic structure of...

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Detalhes bibliográficos
Publicado no:AIDS Res Hum Retroviruses
Main Authors: Alexander, Marina R., Sanders, Rogier W., Moore, John P., Klasse, Per Johan
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651053/
https://ncbi.nlm.nih.gov/pubmed/26086186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2015.0050
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