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Native‐like Env trimers as a platform for HIV‐1 vaccine design

We describe the development and potential use of various designs of recombinant HIV‐1 envelope glycoprotein trimers that mimic the structure of the virion‐associated spike, which is the target for neutralizing antibodies. The goal of trimer development programs is to induce broadly neutralizing anti...

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Bibliografiske detaljer
Udgivet i:Immunol Rev
Main Authors: Sanders, Rogier W., Moore, John P.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299501/
https://ncbi.nlm.nih.gov/pubmed/28133806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12481
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