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Native‐like Env trimers as a platform for HIV‐1 vaccine design

We describe the development and potential use of various designs of recombinant HIV‐1 envelope glycoprotein trimers that mimic the structure of the virion‐associated spike, which is the target for neutralizing antibodies. The goal of trimer development programs is to induce broadly neutralizing anti...

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Detalles Bibliográficos
Publicado en:Immunol Rev
Main Authors: Sanders, Rogier W., Moore, John P.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299501/
https://ncbi.nlm.nih.gov/pubmed/28133806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12481
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