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Cleavage-independent HIV-1 Env trimers engineered as soluble native spike mimetics for vaccine design
Viral glycoproteins mediate entry by pH-activated or receptor-engaged activation and exist in metastable pre-fusogenic states that may be stabilized by directed rational design. As recently reported, the conformationally fixed HIV-1 envelope glycoprotein (Env) trimers in the pre-fusion state (SOSIP)...
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| Wydane w: | Cell Rep |
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| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4637274/ https://ncbi.nlm.nih.gov/pubmed/25892233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.03.047 |
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