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Env exceptionalism – Why are HIV-1 Env glycoproteins atypical immunogens?
Recombinant HIV-1 envelope glycoproteins (Env) of ever increasing sophistication have been evaluated as vaccine candidates for over 30 years. Structurally defined mimics of native trimeric Env (e.g., SOSIP trimers) present multiple epitopes for broadly neutralizing Abs (bNAbs) and their germline pre...
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| Publicado en: | Cell Host Microbe |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7187920/ https://ncbi.nlm.nih.gov/pubmed/32272076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.03.018 |
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