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Autoantibodies induced by chimeric cytokine - HIV envelope glycoprotein immunogens

Cytokines are often used as adjuvants to increase the immunogenicity of vaccines as they can improve the immune response and/or direct it into a desired direction. As an alternative to co-delivering antigens and cytokines separately they can be fused into a composite protein, with the advantage that...

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Detalhes bibliográficos
Main Authors: Isik, Gözde, van Montfort, Thijs, Chung, Nancy P.Y., Moore, John P., Sanders, Rogier W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018769/
https://ncbi.nlm.nih.gov/pubmed/24729614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303401
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